If you have a USB multi-card reader and don’t like how each slot takes up a separate drive letter, the venerable Uwe Sieber has a utility for that: USB Drive Letter Manager.
It lets you move the drive letters around, repress drive letters until you actually insert a card, show a balloon tip when a drive mounts, and lots of other nifty tricks.
And if you’ve ever wanted to eject USB or memory cards from the command line, he has tools for that too.