Application whitelisting is an effective security tool, but a pain to implement and administer. Here’s a very simple tool for it, that works on home versions of Windows as well as pro versions. It’s very simple and possible to defeat, but, arguably, it’s about 90% effective, putting it on par with antivirus and giving you coverage that antivirus will miss. It makes a good companion for antivirus and EMET.
Even grade D+ whitelisting is much better than no whitelisting.